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Catabolic and anabolic phases of osteodystrophy in aged rats.

Abstract:

The aims of this study were to investigate the incidence and characteristics of osteodystrophy that occurred in rats which were maintained until death without experimental intervention. We defined and characterized catabolic and anabolic phases of osteodystrophy, based on the morphology of the cortical bone. During the catabolic phase, large resorption cavities appeared within the cortical bone. During the anabolic phase, progressively increased amounts of new bone was formed, which partially...

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Publication status:
Published

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Publisher copy:
10.1007/s00774-003-0424-8

Authors


Clarke, NM More by this author
Langley-Evans, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Journal of bone and mineral metabolism
Volume:
21
Issue:
5
Pages:
299-306
Publication date:
2003
DOI:
EISSN:
1435-5604
ISSN:
0914-8779
URN:
uuid:e5825bb4-55ae-4989-91a8-d51ba86538af
Source identifiers:
126591
Local pid:
pubs:126591

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