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Neutralizing tumor necrosis factor activity leads to remission in patients with refractory noninfectious posterior uveitis.

Abstract:

OBJECTIVE: To evaluate the efficacy and safety of tumor necrosis factor (TNF) inhibition with the p55 TNF receptor fusion protein (TNFr-Ig) for severe sight-threatening noninfectious posterior segment intraocular inflammation. METHODS: Seventeen patients with refractory noninfectious posterior segment intraocular inflammation received TNFr-Ig by intravenous infusion in this nonrandomized, open-label, pilot study. The primary outcome measure was logMAR visual acuity. Secondary outcome measure...

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Publication status:
Published

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Publisher copy:
10.1001/archopht.122.6.845

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Journal:
Archives of ophthalmology
Volume:
122
Issue:
6
Pages:
845-851
Publication date:
2004-06-05
DOI:
EISSN:
1538-3601
ISSN:
0003-9950
URN:
uuid:e57dbdf1-0328-4478-901b-57b3cc7fd44e
Source identifiers:
7937
Local pid:
pubs:7937

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