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Guselkumab provides durable improvement across psoriatic arthritis disease domains: post hoc analysis of a phase 3, randomised, double-blind, placebo-controlled study

Abstract:

Objective Evaluate long-term guselkumab effectiveness across Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-recognised domains/related conditions of psoriatic arthritis (PsA).

Methods Post hoc analyses used data from DISCOVER-2 (NCT03158285) biologic/Janus-kinase inhibitor-naïve participants with active PsA (≥5 swollen/≥5 tender joints, C-reactive protein ≥0.6 mg/dL), randomised (1:1:1) to guselkumab every 4 or 8 we...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/rmdopen-2023-003977

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-4756-663X
Publisher:
BMJ Publishing Group
Journal:
RMD Open More from this journal
Volume:
10
Issue:
1
Article number:
e003977
Publication date:
2024-03-26
Acceptance date:
2024-02-08
DOI:
EISSN:
2056-5933
Language:
English
Pubs id:
1615630
Local pid:
pubs:1615630
Deposit date:
2024-02-09

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