Metastatic parathyroid carcinoma in the MEN2A syndrome.

Journal article

We report a patient with a metastatic parathyroid carcinoma and medullary carcinoma of the thyroid. This patient represents a variation of the multiple endocrine neoplasia syndrome (MEN) type 2A. There was no evidence of a phaeochromocytoma. The case illustrates the difficulties that may be encountered in localising the source of PTH secretion; the patient underwent four unsuccessful exploratory operations of the neck and mediastinum before further investigations revealed a single metastatic ...

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Authors: Jenkins, P; Satta, M; Simmgen, M; Drake, WM; Williamson, C

• Publication status: Published
• Journal: Clinical endocrinology
• Volume: 47
• Issue: 6
• Pages: 747-751
• Publication date: 1997-12-01
• DOI: 10.1046/j.1365-2265.1997.3421147.x
• EISSN: 1365-2265
• ISSN: 0300-0664
• Language: English
• Keywords: Spinal Neoplasms; Parathyroid Neoplasms; Thoracic Vertebrae; Thyroid Neoplasms; Mutation; Carcinoma; Magnetic Resonance Imaging; Multiple Endocrine Neoplasia Type 2a; Middle Aged; Drosophila Proteins; Receptor Protein-Tyrosine Kinases; Gene Deletion; Humans; Proto-Oncogene Proteins; Male; Proto-Oncogene Proteins c-ret