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Sequential strand exchange by XerC and XerD during site-specific recombination at dif.

Abstract:

Successful segregation of circular chromosomes in Escherichia coli requires that dimeric replicons, produced by homologous recombination, are converted to monomers prior to cell division. The Xer site-specific recombination system uses two related tyrosine recombinases, XerC and XerD, to catalyze resolution of circular dimers at the chromosomal site, dif. A 33-base pair DNA fragment containing the 28-base pair minimal dif site is sufficient for the recombinases to mediate both inter- and intr...

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Publication status:
Published

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Publisher copy:
10.1074/jbc.275.14.9930

Authors


Blakely, GW More by this author
Davidson, AO More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
The Journal of biological chemistry
Volume:
275
Issue:
14
Pages:
9930-9936
Publication date:
2000-04-05
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
URN:
uuid:e53e2393-5cfc-4896-b163-7397268dc22a
Source identifiers:
99746
Local pid:
pubs:99746

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