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Co-modulation of finely tuned high-gamma band activity across hemispheres in Parkinson's disease

Abstract:

Objective: Dopaminergic treatment of patients with Parkinson's disease can be associated with a finely tuned high-gamma (FTG) band oscillation between 60 and 90. Hz in the basal ganglia (BG) nuclei. This activity, together with suppression of excessive neural synchrony in the beta frequency band (15-30. Hz), is hypothesized to contribute to the pro-kinetic effects of dopaminergic medication. Beta activity, which high-gamma replaces, has been shown to be bilaterally coherent, but whether sub-c...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Molecular Medicine
Journal:
Clinical Neurophysiology
Volume:
125
Issue:
4
Pages:
777-785
Publication date:
2014-04-05
DOI:
EISSN:
1872-8952
ISSN:
1388-2457
URN:
uuid:e5104239-da9e-4b85-9a1d-493aab7df473
Source identifiers:
459621
Local pid:
pubs:459621

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