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Journal article

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

Abstract:

We performed a multistage genome-wide association study including 7,683 individuals with pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome-wide significance: rs6971499 at 7q32.3 (LINC-PINT, per-allele odds ratio (OR) = 0.79, 95% confidence interval (CI) 0.74-0.84, P = 3.0 × 10(-12)), rs7190458 at 16q23.1 (BCAR1/CTRB1/CTRB2, OR = 1.46, 95% CI 1.30-1.65, P = 1.1 × 10(-10)), rs9581943 at 13q12.2 (PDX1, OR = 1.15, 95% CI 1.10-1.20, P = 2.4 × 10(-9)) and rs169...

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Publication status:
Published

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Publisher copy:
10.1038/ng.3052

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Journal:
Nature genetics
Volume:
46
Issue:
9
Pages:
994-1000
Publication date:
2014-09-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:e50de6b1-3d25-4ae0-85fe-eed1aef7d37a
Source identifiers:
478882
Local pid:
pubs:478882

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