Umbilical cord leptin predicts neonatal bone mass.

Journal article

Evidence is accumulating that the risk of osteoporosis in later life may be determined in part by environmental influences on bone development during intrauterine and early postnatal life. A potential role for fetal leptin in mediating these effects is suggested by animal studies showing that leptin influences prenatal osteoblast growth and development, and that fetal leptin concentrations are altered by changes in maternal nutrition. In a group of term human infants we reported previously th...

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Authors: Javaid, M; Godfrey, K; Taylor, P; Robinson, S; Crozier, SR

• Publication status: Published
• Journal: Calcified tissue international
• Volume: 76
• Issue: 5
• Pages: 341-347
• Publication date: 2005-05-05
• DOI: 10.1007/s00223-004-1128-3
• EISSN: 1432-0827
• ISSN: 0171-967X
• Language: English
• Keywords: Male; Infant, Newborn; Humans; Bone Density; Absorptiometry, Photon; Birth Weight; Adipose Tissue; Osteoporosis; Leptin; Anthropometry; Female; Body Composition; Fetal Blood; Bone and Bones