- Abstract:
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Background: Artesunate-amodiaquine (AS-AQ) is one of the most widely used artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria. Methods: Individual patient data from AS-AQ clinical trials were pooled using the WorldWide Antimalarial Resistance Network (WWARN) standardised methodology. Risk factors for tr...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.6MB)
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- Publisher copy:
- 10.1186/s12916-015-0301-z
-
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Medicine Journal website
- Volume:
- 13
- Issue:
- 1
- Chapter number:
- ARTN 66
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
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1741-7015
- ISSN:
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1741-7015
- URN:
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uuid:e4d52e32-da19-4b71-80f7-9d0a61936047
- Source identifiers:
-
522723
- Local pid:
- pubs:522723
- Copyright holder:
- The WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group
- Copyright date:
- 2015
- Notes:
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Copyright © 2015 The WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Group; licensee BioMed Central.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Journal article
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data
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Bill and Melinda Gates Foundation
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