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Rapid effector function of circulating CD4+ T cells specific for immunodominant regions of the conserved serine/threonine kinase found in Streptococcus pneumoniae (StkP) in healthy adults.

Abstract:

Streptococcus pneumoniae is an encapsulated bacterium that causes significant global morbidity and mortality. There is emerging evidence that T cells contribute to the immunity that protects humans from S. pneumoniae-associated disease. However, no T-cell epitopes have been identified as yet in this bacterium and there are no data that address the functional nature of T cells specific for pneumococcal-derived epitopes. We sought to define T-cell epitopes in the conserved serine/threonine kina...

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Publication status:
Published

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Authors


Zemenides, S More by this author
Nováková, L More by this author
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Journal:
FEMS immunology and medical microbiology
Volume:
60
Issue:
2
Pages:
113-122
Publication date:
2010-11-05
DOI:
EISSN:
1574-695X
ISSN:
0928-8244
URN:
uuid:e4b53890-4637-44a7-9449-15ca29d2fa03
Source identifiers:
67476
Local pid:
pubs:67476

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