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Thesis

Cellular iron governs the host response to malaria infection and vaccination

Abstract:

Iron deficiency and malaria are two major public health problems with largely overlapping epidemiology, and there is a complex relationship between iron and malaria. Iron deficiency can protect from malaria infection, whereas iron supplementation can increase the risk, and tissue iron loading can disrupt disease tolerance. Immune cells also need iron to support their function and iron deficiency can disrupt immunity. However, it is not known how tolerance or the immune response to malaria ...

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Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Supervisor
ORCID:
0000-0002-8503-6103
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Name:
Wellcome Trust
Funder identifier:
http://dx.doi.org/10.13039/100004440
Grant:
108869/Z/15/Z
Programme:
Wellcome Trust DPhil in Infection, Immunology and Translational Medicine
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2023-04-28

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