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The evolution of homeobox genes: Implications for the study of brain development.

Abstract:

The homeobox gene superfamily includes many genes implicated in brain development in vertebrates; for example, the Otx, Emx, Dmbx, Gbx, En and Hox gene families. We describe the evolutionary history of the homeobox gene superfamily, as inferred from molecular phylogenetics and chromosomal mapping. Studies of amphioxus, a close relative of vertebrates, have proven particularly informative because it has a genome uncomplicated by recent lineage-specific gene duplications and because in situ hyb...

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Publication status:
Published

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Authors


Holland, PW More by this author
Takahashi, T More by this author
Volume:
66
Issue:
4-6
Pages:
484-490
Publication date:
2005-09-05
DOI:
EISSN:
1873-2747
ISSN:
0361-9230
URN:
uuid:e4a3d564-9d7e-4db0-bb39-58680c72f019
Source identifiers:
204407
Local pid:
pubs:204407

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