Journal article
Soluble CD38 significantly prolongs the lifespan of memory B-cell responses.
- Abstract:
-
The development and maintenance of memory B cells (MBC) is dependent on germinal centres (GC) with follicular dendritic cell (FDC) networks. We have previously shown that FDC networks within GC of the spleen express a novel ligand for CD38 and that the administration of soluble CD38 induces an expansion of these cellular structures. We therefore used adoptive transfer studies to investigate whether the expansion of FDC networks with soluble CD38 affected the generation and maintenance of anti...
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- Publication status:
- Published
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- Publisher copy:
- 10.1111/j.1365-2567.2008.02914.x
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Authors
Bibliographic Details
- Journal:
- Immunology
- Volume:
- 125
- Issue:
- 1
- Pages:
- 14-20
- Publication date:
- 2008-09-01
- DOI:
- EISSN:
-
1365-2567
- ISSN:
-
0019-2805
- Source identifiers:
-
6797
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:6797
- UUID:
-
uuid:e47d9d65-b9f4-4384-b7a1-4fb969ebcfbc
- Local pid:
- pubs:6797
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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