Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart.

Journal article

OBJECTIVES: Cardiac fatty acid uptake occurs predominantly via sarcolemmal transporter proteins; fatty acid translocase (FAT/CD36), plasma membrane fatty acid binding protein (FABPpm) and fatty acid transporter proteins (FATP) 1 and 6. We hypothesised that levels of the fatty acid transporters would be reduced in the chronically infarcted rat heart, in parallel with reduced dependence on fatty acid utilisation. METHODS AND RESULTS: In vivo left ventricular ejection fractions, measured using e...

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Authors: Heather, L; Cole, M; Lygate, C; Evans, R; Stuckey, D

• Publication status: Published
• Journal: Cardiovascular research
• Volume: 72
• Issue: 3
• Pages: 430-437
• Publication date: 2006-12-01
• DOI: 10.1016/j.cardiores.2006.08.020
• EISSN: 1755-3245
• ISSN: 0008-6363
• Language: English
• Keywords: Rats, Wistar; Palmitates; Oxidation-Reduction; Biological Markers; Rats; Protein Transport; Fatty Acid-Binding Proteins; Animals; Blotting, Western; Male; Antigens, CD36; Myocardium; Echocardiography; Myocardial Infarction; Fatty Acid Transport Proteins; Stroke Volume; Citrate (si)-Synthase