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Blockade of conditioned taste aversion by scopolamine and N-methyl scopolamine: associative conditioning, not amnesia.

Abstract:

The anticholinergic, scopolamine, consistently disrupts one-trial passive avoidance conditioning but the effects of such drugs on one-trial conditioned taste aversion (CTA) are variable and contradictory. In the present study, treatment of rats with scopolamine impaired the suppression of sucrose intake by post-ingestion administration of lithium chloride (LiCl) in a two-bottle choice test. A similar effect was obtained by using N-methyl scopolamine which penetrates the brain only to a limite...

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Publication status:
Published

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Publisher copy:
10.1007/bf02801970

Authors


Evenden, JL More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Psychopharmacology
Volume:
106
Issue:
2
Pages:
179-188
Publication date:
1992-01-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:e43f0299-b7a8-416d-8fb4-e35c534c619c
Source identifiers:
17396
Local pid:
pubs:17396

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