Journal article
Tracking antigen-specific T-cells during clinical tolerance induction in humans.
- Abstract:
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Allergen immunotherapy presents an opportunity to define mechanisms of induction of clinical tolerance in humans. Significant progress has been made in our understanding of changes in T cell responses during immunotherapy, but existing work has largely been based on functional T cell assays. HLA-peptide-tetrameric complexes allow the tracking of antigen-specific T-cell populations based on the presence of specific T-cell receptors and when combined with functional assays allow a closer assess...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 850.3KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0011028
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 5
- Issue:
- 6
- Article number:
- e11028
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:e4299859-d43f-42d4-8154-76589ca7e6fc
- Local pid:
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pubs:60470
- Source identifiers:
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60470
- Deposit date:
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2012-12-19
Terms of use
- Copyright holder:
- Aslam et al
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Aslam et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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