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Modelling the optimal dosing schedule for artemether-lumefantrine chemoprophylaxis against malaria

Abstract:

Objective Antimalarial chemoprophylaxis for high risk groups in endemic areas of Southeast Asia has the potential to reduce malaria transmission and accelerate elimination. However, the optimal choice of medication and dosing for many potential candidates is not clear. For a planned randomised controlled trial of prophylaxis for forest goers in Cambodia, artemether-lumefantrine (AL) was selected because of its ongoing efficacy and excellent tolerability and safety. As AL had not been used bef...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13104-022-06212-y

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-1897-1978
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-5355-0562
More from this funder
Name:
Global Fund to Fight AIDS, Tuberculosis and Malaria
Publisher:
BioMed Central
Journal:
BMC Research Notes More from this journal
Volume:
15
Article number:
313
Publication date:
2022-10-02
Acceptance date:
2022-09-19
DOI:
EISSN:
1756-0500
Pmid:
36184602
Language:
English
Keywords:
Pubs id:
1281663
Local pid:
pubs:1281663
Deposit date:
2022-11-08

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