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The role of the thymus in allogeneic hematopoietic stem cell transplantation.

Abstract:

Allogeneic haematopoietic stem cell transplantation (HSCT) is used to treat an increasing number of congenital and acquired disorders of the haematopoietic system. Even though cytoreductive conditioning regimens vary in intensity, all clinically used protocols invariably cause side effects that compromise transiently or long-term the response of the natural and the adaptive immune systems. However, in the context of the reconstruction of immunity, the generation of naïve T cells constitutes a...

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Publisher copy:
10.4414/smw.2010.13051

Authors


Krenger, W More by this author
Holländer, GA More by this author
Journal:
Swiss medical weekly
Volume:
140
Pages:
w13051
Publication date:
2010
DOI:
EISSN:
1424-3997
ISSN:
1424-7860
URN:
uuid:e3cb0c2e-469f-4f28-b869-d24c3628e9be
Source identifiers:
309050
Local pid:
pubs:309050

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