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Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.

Abstract:

Background

Artemisinin resistance, linked to polymorphisms in the Kelch gene on chromosome 13 of Plasmodium falciparum (k13), has outpaced containment efforts in South East Asia. For national malaria control programmes in the region, it is important to establish a surveillance system which includes monitoring for k13 polymorphisms associated with the clinical phenotype.

Methods

Between February and December 2013, parasite clearance was assessed in 35 patients with...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12936-017-2128-x

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
ORCID:
0000-0002-0383-9624
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
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Department for International Development More from this funder
Wellcome Trust More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
16
Issue:
1
Pages:
480
Publication date:
2017-11-05
Acceptance date:
2017-11-18
DOI:
EISSN:
1475-2875
Pubs id:
pubs:803750
URN:
uri:e38f9371-76f9-4b7c-8d63-83e10519a607
UUID:
uuid:e38f9371-76f9-4b7c-8d63-83e10519a607
Local pid:
pubs:803750

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