- Abstract:
-
Precursors of NGF have been shown to be the predominant forms of this neurotrophin in human brain and peripheral tissues, and proNGF has been shown recently to preferentially bind p75NTR with high affinity. In our studies of human and rat skin and nerve extracts, a 53 kDa band was detected by Western blot using antibodies against rhNGF or prepro-NGF (-91 to -60), that could correspond to a previously described modified prepro-NGF-like molecule. The relative optical intensity of the 53-kDa ban...
Expand abstract - Publisher copy:
- 10.1046/j.1529-8027.2002.02024.x
-
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- Journal:
- Journal of the peripheral nervous system : JPNS
- Volume:
- 7
- Issue:
- 3
- Pages:
- 190-197
- Publication date:
- 2002-09-05
- DOI:
- EISSN:
-
1529-8027
- ISSN:
-
1085-9489
- URN:
-
uuid:e37ab7c7-e7fe-4f7d-9ba9-20b43de3d37a
- Source identifiers:
-
365798
- Local pid:
- pubs:365798
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin.
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