PCR-SSO typing in HLA-disease association studies.

Journal article

Associations between a large number of diseases and markers within the major histocompatibility complex (MHC) have been described. In particular, susceptibility to several autoimmune disorders, including type I diabetes mellitus and rheumatoid arthritis, is linked to genes within the MHC and strong population associations are demonstrable between certain HLA class II alleles and these conditions. Genetic mapping of HLA susceptibility loci has traditionally relied on the use of phenotypic mark...

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Authors: Wordsworth, P

• Publication status: Published
• Journal: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics
• Volume: 18
• Issue: 1-2
• Pages: 139-146
• Publication date: 1991-01-01
• DOI: 10.1111/j.1744-313x.1991.tb00013.x
• EISSN: 1365-2370
• ISSN: 0960-7420
• Language: English
• Keywords: Diabetes Mellitus, Type 1; Alleles; Genetic Markers; Pemphigus; Polymerase Chain Reaction; DNA Probes; HLA Antigens; Autoimmune Diseases; Arthritis, Rheumatoid; Celiac Disease; Histocompatibility Testing; Oligodeoxyribonucleotides; Humans