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Subcellular localisation of vitamin B12 during absorption in the guinea-pig ileum.

Abstract:

The subcellular distribution of vitamin B12 was studied during its absorption in the guinea-pig ileum. Animals were fed either (57Co) or (58Co) cyanocobalamin and killed two or four hours later. At two hours labelled cyanocobalamin was concentrated in brush border and lysosomal fractions of ileal homogenates, with some remaining in the sample layer. In contrast, at four hours labelled cyanocobalamin was concentrated predominantly in the cytosol with much smaller peaks in the brush border and ...

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Publication status:
Published

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Publisher copy:
10.1136/gut.22.8.617

Authors


Jenkins, WJ More by this author
Jewell, DP More by this author
Taylor, KB More by this author
Journal:
Gut
Volume:
22
Issue:
8
Pages:
617-622
Publication date:
1981-08-05
DOI:
EISSN:
1468-3288
ISSN:
0017-5749
URN:
uuid:e35cf1d5-04a7-4d69-9bcf-71d6c0b81533
Source identifiers:
165732
Local pid:
pubs:165732

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