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Journal article

X-ray microanalysis of cell elements in normal and cystic fibrosis jejunum: evidence for chloride secretion in villi.

Abstract:

BACKGROUND and AIMS: Cystic fibrosis transmembrane conductance regulator (CFTR) is an adenosine 3',5'-cyclic monophosphate-dependent chloride channel that is defective in cystic fibrosis. The aims of this study were to determine if defective apical chloride secretion in the intestine of patients with cystic fibrosis alters the intracellular electrolyte milieu and to examine the geographical localization of CFTR in the normal intestine. METHODS: The content of intracellular elements was assess...

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Publication status:
Published

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Journal:
Gastroenterology
Volume:
110
Issue:
2
Pages:
411-418
Publication date:
1996-02-05
DOI:
EISSN:
1528-0012
ISSN:
0016-5085
URN:
uuid:e3474811-9442-4530-b2c4-41fee88333e5
Source identifiers:
9951
Local pid:
pubs:9951

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