Journal article

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Abstract:: Elevated blood pressure is the leading heritable risk factor for cardiovascular disease worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) among UK Biobank participants of European ancestry with independent replication in other cohorts, and robust validation of 107 independent loci. We also identify new independent variants at 11 previously reported blood pressure loci. Combined with results from a range of in silico functional analyses and wet be...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Warren, H., Evangelou, E., Cabrera, C., Gao, H., Ren, M., Mifsud, B., Ntalla, I., Surendran, P., Liu, C., Cook, J., Kraja, A., Drenos, F., Loh, M., Verweij, N., Marten, J., Karaman, I., Lepe, M., O'Reilly, P., Knight, J., … UK Biobank CardioMetabolic Consortium BP working group. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 43, 403–415.

MLA Style

Warren, H., et al. “Genome-Wide Association Analysis Identifies Novel Blood Pressure Loci and Offers Biological Insights into Cardiovascular Risk.” Nature Genetics, vol. 43, Nature Publishing Group, 2017, pp. 403–15.

Chicago Style

Warren, H, E Evangelou, C Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, et al. 2017. “Genome-Wide Association Analysis Identifies Novel Blood Pressure Loci and Offers Biological Insights into Cardiovascular Risk.” Nature Genetics 43: 403–15.
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Publisher copy:: 10.1038/ng.3768

Authors

+ Warren, H More by this author

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+ Evangelou, E More by this author

Role:

Author

+ Cabrera, C More by this author

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+ Gao, H More by this author

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+ Ren, M More by this author

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Author

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Funding

+ British Heart Foundation More from this funder

Funding agency for:

Farrall, M

Grant:

RE/13/1/30181

SP/13/2/30111

+ Wellcome Trust More from this funder

Funding agency for:

Farrall, M

Grant:

RE/13/1/30181

109863/Z/15/Z

+ Horizon 2020 More from this funder

Grant:

654241

+ Marie Sklodowska-Curie GF More from this funder

Grant:

661395

+ European Research Council More from this funder

Grant:

268834

More funders...

Bibliographic Details

Publisher:: Nature Publishing Group
Journal:: Nature Genetics More from this journal
Volume:: 43
Pages:: 403–415
Publication date:: 2017-01-01
Acceptance date:: 2016-12-14
DOI:: 10.1038/ng.3768
ISSN:: 1546-1718

Item Description

Language:: English
Keywords:: Journal Article
Pubs id:: pubs:675069
UUID:: uuid:e321fc68-a0fd-4853-9f0e-0340e31d4227
Local pid:: pubs:675069
Source identifiers:: 675069
Deposit date:: 2017-02-15

Terms of use

Copyright holder:: Nature America, Inc
Copyright date:: 2017
Notes:: © 2017 Nature America, Inc., part of Springer Nature. All rights reserved.

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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