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Ethical and scientific considerations on the establishment of a controlled human infection model for schistosomiasis in Uganda: report of a stakeholders’ meeting held in Entebbe, Uganda

Subtitle:
Open letter
Abstract:

Controlled human infection (CHI) models are gaining recognition as an approach to accelerating vaccine development, for use in both non-endemic and endemic populations: they can facilitate identification of the most promising candidate vaccines for further trials and advance understanding of protective immunity. Helminths present a continuing health burden in sub-Saharan Africa. Vaccine development for these complex organisms is particularly challenging, partly because protective responses ar...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.12688/aasopenres.12841.2

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ORCID:
0000-0003-2818-9549
Roestenberg, M More by this author
Angumya, F More by this author
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Publisher:
F1000Research Publisher's website
Journal:
AAS Open Research Journal website
Volume:
1
Pages:
2
Publication date:
2018-08-06
Acceptance date:
2018-08-06
DOI:
EISSN:
2515-9321
Pubs id:
pubs:890982
URN:
uri:e31fb9ab-0534-4bf8-a441-2d1964c59b1e
UUID:
uuid:e31fb9ab-0534-4bf8-a441-2d1964c59b1e
Local pid:
pubs:890982

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