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Journal article

Intragraft interleukin-4 mRNA expression after short-term CD154 blockade may trigger delayed development of transplant arteriosclerosis in the absence of CD8+ T cells.

Abstract:

BACKGROUND: It has recently been shown that, although anti-CD154 induces CD4+ T-cell tolerance, it is unable to prevent allograft rejection mediated by CD8+ T cells. We have also shown that anti-CD154 monotherapy does not protect the graft from the development of transplant arteriosclerosis even in the absence of CD8+ T cells. This study was designed to investigate and characterize possible mechanisms responsible for the development of transplant arteriosclerosis after CD154 blockade in the a...

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Publication status:
Published

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Journal:
Transplantation
Volume:
70
Issue:
6
Pages:
955-963
Publication date:
2000-09-01
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
Source identifiers:
135920
Language:
English
Keywords:
Pubs id:
pubs:135920
UUID:
uuid:e31f50a1-eaec-4d80-9735-d6298d94445a
Local pid:
pubs:135920
Deposit date:
2012-12-19

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