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Journal article

Combination of RTS,S and Pfs25-IMX313 induces a functional antibody response against malaria infection and transmission in mice

Abstract:

The last two decades saw a dramatic reduction in malaria incidence rates, but this decrease has been stalling recently, indicating control measures are starting to fail. An effective vaccine, particularly one with a marked effect on disease transmission, would undoubtedly be an invaluable tool for efforts to control and eliminate malaria. RTS,S/AS01, the most advanced malaria vaccine to date, targets the parasite before it invades the liver and has the potential to prevent malaria disease as ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fimmu.2018.02780

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
Jenner Institute
Role:
Author
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PATH’s Malaria Vaccine Initiative More from this funder
National Institutes of Health More from this funder
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Immunology Journal website
Volume:
9
Pages:
2780
Publication date:
2018-12-04
Acceptance date:
2018-11-12
DOI:
EISSN:
1664-3224
Pubs id:
pubs:952817
URN:
uri:e3190467-6aee-4ed1-ba2e-a0b9cef912b9
UUID:
uuid:e3190467-6aee-4ed1-ba2e-a0b9cef912b9
Local pid:
pubs:952817

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