In vitro proliferative responses of human peripheral blood mononuclear cells to non-recall antigens.

Journal article

Primary in vitro proliferative responses of naive T cells to antigens other than superantigens and alloantigens have been little studied. Two tissue culture techniques have been reported which support in vitro antigen priming of T cells. These methods require various degrees of cellular manipulation and culture vessels other than standard microtitre plates. We report here that primary proliferative responses to non-recall antigens can be readily obtained using unselected human PBMC prepared f...

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Authors: Young, J; Daser, A; Beverley, P

• Journal: Journal of immunological methods
• Volume: 182
• Issue: 2
• Pages: 177-184
• Publication date: 1995-06-01
• DOI: 10.1016/0022-1759(95)00046-d
• EISSN: 1872-7905
• ISSN: 0022-1759
• Language: English
• Keywords: Antigens; Dogs; Immunologic Techniques; T-Lymphocytes; Leukocytes, Mononuclear; Humans; Cytochrome c Group; Lymphocyte Activation; Animals; Fetal Blood; Infant, Newborn; Mollusca; Rabies Vaccines; Adult; Hemocyanin