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Journal article

The polyAT, intronic IVS11-6 and Lys939Gln XPC polymorphisms are not associated with transitional cell carcinoma of the bladder.

Abstract:

Chemical carcinogens from cigarette smoking and occupational exposure are risk factors for bladder transitional cell carcinoma (TCC). The Xeroderma Pigmentosum Group C (XPC) gene is essential for repair of bulky adducts from carcinogens. The Xeroderma Pigmentosum Group C gene polymorphisms may alter DNA repair capacity (DRC), thus giving rise to genetic predisposition to bladder cancer. Recent studies have demonstrated linkage disequilibrium between three polymorphisms in the XPC gene (polyAT...

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Publication status:
Published

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Publisher copy:
10.1038/sj.bjc.6602616

Authors


Barrett, JH More by this author
Bishop, DT More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology, CRUK/MRC Ox Inst for Radiation Oncology
Journal:
British journal of cancer
Volume:
92
Issue:
12
Pages:
2262-2265
Publication date:
2005-06-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:e2dc3ae6-0497-474e-884a-b5260ba9fb18
Source identifiers:
131262
Local pid:
pubs:131262

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