Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments.

Journal article

OBJECTIVE: To describe the potential benefits and harms of oseltamivir by reviewing all clinical study reports (or similar document when no clinical study report exists) of randomised placebo controlled trials and regulatory comments ("regulatory information"). DESIGN: Systematic review of regulatory information. DATA SOURCES: Clinical study reports, trial registries, electronic databases, regulatory archives, and correspondence with manufacturers. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: ...

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Authors: Jefferson, T; Jones, M; Doshi, P; Spencer, E; Onakpoya, I

• Publication status: Published
• Journal: BMJ (Clinical research ed.)
• Volume: 348
• Issue: apr09 2
• Pages: g2545
• Publication date: 2014-01-01
• DOI: 10.1136/bmj.g2545
• EISSN: 1756-1833
• ISSN: 0959-8138
• Language: English
• Keywords: Treatment Outcome; Humans; Randomized Controlled Trials as Topic; Antiviral Agents; Child; Influenza, Human; Nausea; Headache; Adult; Oseltamivir; Kidney Diseases; Vomiting; Age Factors