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Identification of new genetic risk factors for prostate cancer.

Abstract:

There is evidence that a substantial part of genetic predisposition to prostate cancer (PCa) may be due to lower penetrance genes which are found by genome-wide association studies. We have recently conducted such a study and seven new regions of the genome linked to PCa risk have been identified. Three of these loci contain candidate susceptibility genes: MSMB, LMTK2 and KLK2/3. The MSMB and KLK2/3 genes may be useful for PCa screening, and the LMTK2 gene might provide a potential therapeuti...

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Publication status:
Published

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Publisher copy:
10.1038/aja.2008.18

Authors


Kote-Jarai, Z More by this author
Al Olama, AA More by this author
Jugurnauth, SK More by this author
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Journal:
Asian journal of andrology
Volume:
11
Issue:
1
Pages:
49-55
Publication date:
2009-01-05
DOI:
EISSN:
1745-7262
ISSN:
1008-682X
URN:
uuid:e2a9217a-7b87-4292-a8fc-a7ee0bee07ed
Source identifiers:
120691
Local pid:
pubs:120691

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