Abstract:

The neuropathology of degenerative brain and spinal cord diseases is briefly reviewed. These are diseases in which selected populations of neurons die progressively, giving rise to progressive diseases affecting cognitive or motor functions. They are associated with the build-up in the CNS of abnormal protein aggregates. Many are genetically determined in at least some cases and recent discovery of the genes involved has enabled animal models to be developed that allow preventive or treatment...

Expand abstract

Collapse abstract

Metrics

---