- Abstract:
-
Spinocerebellar ataxia 6 (SCA6) is a hereditary disease characterized by a trinucleotide repeat expansion in the CACNA1A gene and late-onset bilateral cerebellar atrophy. It is unclear if there is significant pathology outside of the cerebellum. We used transcranial magnetic stimulation to assess sensorimotor cortical circuits and cortical plasticity in 8 SCA6 patients and 8 age-matched controls. Behavioral performance was assessed using a rhythmic tapping task. Neurophysiological measures of...
Expand abstract - Publisher copy:
- 10.1002/mds.21847
-
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- Journal:
- Movement disorders : official journal of the Movement Disorder Society
- Volume:
- 23
- Issue:
- 3
- Pages:
- 378-385
- Publication date:
- 2008-02-05
- DOI:
- EISSN:
-
1531-8257
- ISSN:
-
0885-3185
- URN:
-
uuid:e27f0a7f-48e1-4234-9b28-1f5bbdc37ab6
- Source identifiers:
-
243257
- Local pid:
- pubs:243257
- Language:
- English
- Keywords:
- Copyright date:
- 2008
Journal article
Prolonged cortical silent period but normal sensorimotor plasticity in spinocerebellar ataxia 6.
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