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Cortical function in progressive lower motor neuron disorders and amyotrophic lateral sclerosis: a comparative PET study.

Abstract:

OBJECTIVE: To compare cortical function at rest and during limb movement in patients with progressive lower motor neuron degeneration (LMND) and amyotrophic lateral sclerosis (ALS). METHODS: PET was used to measure regional cerebral blood flow (rCBF) in five patients with progressive LMND, six patients with classic ALS with a similar degree of motor impairment, and six age-matched control subjects; measurements were taken in the resting state and while subjects moved a joystick with their rig...

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Publication status:
Published

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Publisher copy:
10.1212/wnl.44.6.1101

Authors


Brooks, DJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Rothwell, JC More by this author
Frackowiak, RS More by this author
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Journal:
Neurology
Volume:
44
Issue:
6
Pages:
1101-1110
Publication date:
1994-06-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:e24cc9e3-bba8-4e1c-8602-f385670704f2
Source identifiers:
23418
Local pid:
pubs:23418

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