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In situ hybridization of human immunodeficiency virus (HTLV-III) in cryostat sections of lymph nodes of lymphadenopathy syndrome patients.

Abstract:

The presence of human immunodeficiency virus (HIV, or HTLV-III) genome sequence was investigated by means of in situ hybridization in cryostat sections of lymph nodes from lymphadenopathy syndrome (LAS) patients. The technique employed involved the modification of the DNA probe by chemical insertion of an antigenic sulfone group in cytosine moieties and the visualization of DNA by a double-antibody immunohistochemical reaction. The hybrid formation was revealed in five out of ten cases: in al...

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Publisher copy:
10.1002/jmv.1890220204

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Lab Sciences
Role:
Author
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Journal:
Journal of medical virology More from this journal
Volume:
22
Issue:
2
Pages:
135-142
Publication date:
1987-06-01
DOI:
EISSN:
1096-9071
ISSN:
0146-6615
Language:
English
Keywords:
Pubs id:
pubs:486752
UUID:
uuid:e2309c54-bc79-4e81-a290-e0a04f5b8acc
Local pid:
pubs:486752
Source identifiers:
486752
Deposit date:
2014-10-23

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