Objectives: To determine the skeletal safety and efficacy of long term (≥10 years) alendronate use in patients with osteoporosis.Expand abstract
Design: Open register based cohort study containing two nested case control studies.
Setting: Nationwide study of population of Denmark.
Participants: 61 990 men and women aged 50-94 at the start of treatment, who had not previously taken alendronate, 1996-2007.
Interventions: Treatment with alendronate.
Main outcome measures: Incident...
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher's version
- Copyright holder:
- Abrahamsen et al.
- Copyright date:
- This is the publisher's version of the article. The final version is available online from BMJ Publishing Group at: [10.1136/bmj.i3365]