Journal article
A multiple timescale analysis of a mathematical model of the Wnt/β−catenin signalling pathway
- Abstract:
-
The Wnt signalling pathway is involved in stem cell maintenance, differentiation and tissue development. Its disregulation has also been implicated in many cancers. β-catenin is a protein that regulates both transcription of many genes and cell-cell adhesion; in response to an external Wnt stimulus the intracellular levels of β-catenin are controlled by the proteins which make up the Wnt/β-catenin signalling pathway. In this paper we present a systematic asymptotic analysis of an existing mod...
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- Publisher copy:
- 10.1007/s00285-009-0262-y
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Authors
Bibliographic Details
- Journal:
- Journal of mathematical biology
- Volume:
- 60
- Issue:
- 1
- Pages:
- 131-160
- Publication date:
- 2009-09-01
- DOI:
Item Description
- UUID:
-
uuid:e1f09c2e-7e5b-4106-b5b2-c8508ccf7290
- Local pid:
- cs:5032
- Deposit date:
- 2015-03-31
Terms of use
- Copyright date:
- 2009
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