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Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study

Abstract:

BACKGROUND: Depression and chronic pain are the two most important causes of disability (Global Burden of Disease Study 2013). They occur together more frequently than expected and both conditions have been shown to be co-morbid with cardiovascular disease. Although shared socio-demographic risk factors (e.g. gender, deprivation) might explain the co-morbidity of these three conditions, we hypothesised that these three long-term, highly prevalent conditions co-occur and may be due to shared f...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0170653

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Department:
Oxford, MSD, Primary Care Health Sciences
Hocking, LJ More by this author
Torrance, N More by this author
Campbell, A More by this author
Padmanabhan, S More by this author
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
12
Issue:
2
Pages:
Article: e0170653
Publication date:
2017
DOI:
ISSN:
1932-6203
Pubs id:
pubs:682299
URN:
uri:e1e9970c-a61e-4dd9-acd1-f0f69781d1d2
UUID:
uuid:e1e9970c-a61e-4dd9-acd1-f0f69781d1d2
Local pid:
pubs:682299
Language:
English
Keywords:

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