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Journal article

Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma.

Abstract:

PURPOSE: Transitional cell carcinoma (TCC) is a pan-urothelial disease characterized by multiplicity. Although little is known about the molecular events in upper-tract TCC, similar carcinogenic mechanisms are thought to occur throughout the urinary tract. However, we have previously shown that distinct patterns of microsatellite instability occur in upper and lower urinary tract TCC, suggesting biologic differences between these tumors. Here we investigate the extent of promoter hypermethyl...

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Publication status:
Published

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Publisher copy:
10.1200/jco.2005.03.163

Authors


Azzouzi, AR More by this author
Feeley, KM More by this author
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Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume:
23
Issue:
13
Pages:
2903-2910
Publication date:
2005-05-05
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:e1c5f159-c9b1-41cf-a4bf-d436b35483bb
Source identifiers:
120682
Local pid:
pubs:120682

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