Journal article
Amino acid functionalisation using the 2-phosphaethynolate anion. A facile route to (phosphanyl)carbonyl-amino acids
- Abstract:
- We describe the reactivity of the 2-phosphaethynolate anion (PCO(-)) towards enantiomerically pure α-amino acids (AAs) resulting in the formation of novel salts of phosphinecarboxamides bearing chiral functionalities. These transformations occurred quantitatively with all but one of the amino acids trialled (the basic amino acid arginine was found to be unreactive). The resulting ionic species can be readily protonated to afford N-(phosphanyl)carbonyl-amino acids, a novel group of amino acids bearing primary phosphine functionalities.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Accepted manuscript, pdf, 300.4KB)
-
- Publisher copy:
- 10.1039/c7cc01285c
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Jupp, A
Grant:
G0601617
Conselho Nacional de Desenvolvimento
Cientı´fico e Tecnolo´gico
More from this funder
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Chemical Communication Journal website
- Volume:
- 53
- Issue:
- 52
- Pages:
- 7092-7095
- Publication date:
- 2017-06-08
- Acceptance date:
- 2017-06-07
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
- Source identifiers:
-
702389
Item Description
- Language:
- English
- Pubs id:
-
pubs:702389
- UUID:
-
uuid:e1b8a40f-c388-47d4-bf2d-6989c7fcaa9e
- Local pid:
- pubs:702389
- Deposit date:
- 2017-07-03
Terms of use
- Copyright holder:
- © Faria, Jupp, & Goicoechea, 2017
- Copyright date:
- 2017
- Notes:
- This is the author accepted manuscript following peer review version of the article. The final version is available online from Royal Society of Chemistry at: 10.1039/c7cc01285c
If you are the owner of this record, you can report an update to it here: Report update to this record