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A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy.

Abstract:

BACKGROUND: There is no safe, practical, and effective treatment for pregnant women infected with multidrug-resistant Plasmodium falciparum. METHODS: We recruited pregnant Karen women in the second or third trimesters of pregnancy who had uncomplicated falciparum malaria for a randomized, open-label trial with a restricted sequential trial design of 7 days of supervised quinine (SQ7) versus 3 days of artesunate-atovaquone-proguanil (AAP). RESULTS: Eight-one pregnant women entered the study b...

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Publication status:
Published

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Publisher copy:
10.1086/432551

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Ashley, EA More by this author
Barends, M More by this author
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Journal:
The Journal of infectious diseases
Volume:
192
Issue:
5
Pages:
846-853
Publication date:
2005-09-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:e194bce7-ab63-45a1-b895-4f9c08c7fdf3
Source identifiers:
19446
Local pid:
pubs:19446

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