Acute management of dengue shock syndrome: a randomized double-blind comparison of 4 intravenous fluid regimens in the first hour.

Journal article

Dengue hemorrhagic fever is an important cause of morbidity among Asian children, and the more severe dengue shock syndrome (DSS) causes a significant number of childhood deaths. DSS is characterized by a massive increase in systemic capillary permeability with consequent hypovolemia. Fluid resuscitation is critical, but as yet there have been no large trials to determine the optimal fluid regimen. We undertook a randomized blinded comparison of 4 fluids (dextran, gelatin, lactated Ringer's, ...

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Authors: Ngo, N; Cao, X; Kneen, R; Wills, B; Nguyen, V

• Publication status: Published
• Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
• Volume: 32
• Issue: 2
• Pages: 204-213
• Publication date: 2001-01-01
• DOI: 10.1086/318479
• EISSN: 1537-6591
• ISSN: 1058-4838
• Language: English
• Keywords: Adolescent; Dengue Hemorrhagic Fever; Regression Analysis; Gelatin; Resuscitation; Humans; Dextrans; Pulse; Female; Male; Fluid Therapy; Isotonic Solutions; Child; Infant; Child, Preschool; Time Factors; Double-Blind Method; Sodium Chloride