- Abstract:
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In part I, the distribution of pyrimidine bases in ox spleen deoxyribonucleic acid (DNA) have been investigated by treating the freshly prepared nucleic acid with hydrochloric acid in the presence of ethyl mercaptan. By this means the purine bases ware cleaved and a polymeric mercaptalated deoxyribonucleic acid (MDNA) was obtained in which diethylmercaptal groups replaced the purines. The vicinal hydroxyl groups in acyclic mercaptalated residues rendered MDNA labile to alkaline scission. T...
Expand abstract - Peer review status:
- Peer Reviewed
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- Publication date:
- 1956
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Local pid:
- polonsky:9:23
- Copyright holder:
- Ward, Peter Frank Villiers
- Copyright date:
- 1956
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
Thesis
Some structural and biochemical studies of nucleic acids
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This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
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