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Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter.

Abstract:

The pathogenesis of bipolar disorder may involve, at least in part, aberrations in serotonergic neurotransmission. Hence, serotonergic genes are attractive targets for association studies of bipolar disorder. We have reviewed the literature in this field. It is difficult to synthesize results as only one polymorphism per gene was typically investigated in relatively small samples. Nevertheless, suggestive associations are available for the 5HT2A receptor and the serotonin transporter genes. W...

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Publication status:
Published

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Publisher copy:
10.1080/07853890500357428

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Journal:
Annals of medicine
Volume:
37
Issue:
8
Pages:
590-602
Publication date:
2005-01-01
DOI:
EISSN:
1365-2060
ISSN:
0785-3890
URN:
uuid:e15aaf7e-cb6c-40da-a1ee-c164a9cb96c9
Source identifiers:
168252
Local pid:
pubs:168252

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