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Does class switching contribute to remission in bullous pemphigoid?

Abstract:

A correlation between the titre of circulating IgG autoantibodies and disease activity has been difficult to demonstrate in bullous pemphigoid. We postulate that isotype switching from "inflammatory" IgG1 to "blocking" IgG4 subclass antibodies might contribute to disease remission. We studied 16 patients with bullous pemphigoid, 3 patients with cicatricial pemphigoid and 2 patients with epidermolysis bullosa acquisita at different stages of the disease. The titres of IgG subclass and total Ig...

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Publication status:
Published

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Publisher copy:
10.1080/000155599750011345

Authors


Wojnarowska, F More by this author
Journal:
Acta dermato-venereologica
Volume:
79
Issue:
2
Pages:
127-131
Publication date:
1999-03-05
DOI:
EISSN:
1651-2057
ISSN:
0001-5555
URN:
uuid:e159c52a-750a-40d9-b53b-e7a56af9c6da
Source identifiers:
25399
Local pid:
pubs:25399

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