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Journal article

Effect of short-term macrophage depletion in the development of posterior capsule opacification in rodents.

Abstract:

AIM: To evaluate the role of macrophages in the development of posterior capsule opacification (PCO). METHODS: For this purpose, an extracapsular lens extraction was performed in 18 consecutive Sprague-Dawley rats. Animals were treated with liposomal clodronate (Cl(2)MDP-lip-treated group, n = 10) or phosphate-buffered saline (PBS) (control group, n = 8) 1 day preoperatively and on the first day postoperatively, and sacrificed 3 days postoperatively. Masked clinical, light microscopy and imm...

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Publication status:
Published

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Publisher copy:
10.1136/bjo.2007.130518

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NPEU
McKinnon, AD More by this author
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Journal:
The British journal of ophthalmology
Volume:
92
Issue:
11
Pages:
1528-1533
Publication date:
2008-11-05
DOI:
EISSN:
1468-2079
ISSN:
0007-1161
URN:
uuid:e155c0bf-cbfb-43de-a0a3-9431feaacb01
Source identifiers:
236748
Local pid:
pubs:236748

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