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Production and characterisation of a collagen-calcium phosphate composite for use as a bone substitute

Abstract:

A composite for use as a bone substitute has been produced by the precipitation of calcium phosphate onto a collagen matrix. A collagen sheet is used as a membrane separating reservoirs of calcium and phosphate ions. The ions diffuse through the membrane and calcium phosphate precipitation occurs on and within the collagen matrix.Composites containing octacalcium phosphate or hydroxyapatite have been produced by varying the precipitation pH. If the correct balance of phosphate and calcium ion...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Materials
Role:
Author
Publisher:
Materials Research Society
Volume:
550
Pages:
273-278
Publication date:
1999-01-01
ISSN:
0272-9172
URN:
uuid:e147671f-28e5-4949-ba76-ed1dc835154b
Source identifiers:
27348
Local pid:
pubs:27348
ISBN:
1-55899-456-4

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