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Journal article

The influence of IS1301 in the capsule biosynthesis locus on meningococcal carriage and disease.

Abstract:

Previously we have shown that insertion of IS1301 in the sia/ctr intergenic region (IGR) of serogroup C Neisseria meningitidis (MenC) isolates from Spain confers increased resistance against complement-mediated killing. Here we investigate the significance of IS1301 in the same location in N. meningitidis isolates from the UK. PCR and sequencing was used to screen a collection of more than 1500 meningococcal carriage and disease isolates from the UK for the presence of IS1301 in the IGR. IS13...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0009413

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Institution:
University of Oxford
Role:
Author
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European Molecular Biology Organization More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
2
Pages:
e9413
Publication date:
2010-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:e13b0da8-2b46-416e-b734-94597da39bd5
Source identifiers:
210540
Local pid:
pubs:210540

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