Statistical analysis of the bioassay of continuous carcinogens.
In an experiment consisting of the continuous constant application of various carcinogenic regimens to a pure strain of experimental animals for a long period, the cancer incidence rates so caused may be studied and compared by the fit of an appropriate class of statistical distributions. In this paper we show that a Weibull distribution in which the age-specific cancer incidence rate rises as a power of time since first risk is more appropriate than a lognormal distribution. If the Weibull f...Expand abstract
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