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Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23.

Abstract:

Blast-1 is a human activation-associated glycoprotein expressed on the surface of leukocytes. Analysis of a translated sequence from a Blast-1 cDNA reveals a single hydrophobic sequence which could traverse the plasma membrane, but is devoid of charged residues that might represent a cytoplasmic tail. Consistent with this characteristic, Blast-1 is demonstrated here to be anchored to the cell surface through a glycosyl-phosphatidylinositol (GPI)-containing lipid. Comparison of Blast-1 to othe...

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Publisher copy:
10.1084/jem.169.3.1087

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Journal:
The Journal of experimental medicine
Volume:
169
Issue:
3
Pages:
1087-1099
Publication date:
1989-03-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:e0ed4d0e-b9a7-4e6c-a7a5-436e4cadf14c
Source identifiers:
482707
Local pid:
pubs:482707

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