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Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23.

Abstract:

Blast-1 is a human activation-associated glycoprotein expressed on the surface of leukocytes. Analysis of a translated sequence from a Blast-1 cDNA reveals a single hydrophobic sequence which could traverse the plasma membrane, but is devoid of charged residues that might represent a cytoplasmic tail. Consistent with this characteristic, Blast-1 is demonstrated here to be anchored to the cell surface through a glycosyl-phosphatidylinositol (GPI)-containing lipid. Comparison of Blast-1 to othe...

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Publisher copy:
10.1084/jem.169.3.1087

Authors


Staunton, DE More by this author
Fisher, RC More by this author
LeBeau, MM More by this author
Lawrence, JB More by this author
Barton, DE More by this author
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Journal:
The Journal of experimental medicine
Volume:
169
Issue:
3
Pages:
1087-1099
Publication date:
1989-03-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:e0ed4d0e-b9a7-4e6c-a7a5-436e4cadf14c
Source identifiers:
482707
Local pid:
pubs:482707

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